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Electrical Measurement and Simulation of the Human Brain

Date:  Thursday, March 1st, 2018

Speaker:  Don M. Tucker, Ph.D, Professor of Psychology, Director of the Neuroinformatics Center, University of Oregon
Head of Clinical Science, Philips Neuro egi.com
CEO, NADA (Neural Analog-to-Digital Approximation) nadaweb.net

Date:  Thursday, March 1st, 2018
Time: 4:00-5:00pm
Location: 100 Willamette Hall

Abstract:

The electroencephalogram or EEG has been an important research and clinical tool for the last 75 years.  Recent advances in localizing the EEG to the electrical fields of the cortex have been achieved through dense electrode arrays, specifying the geometry of head tissues with MRI and CT, and measuring the conductivity of head tissues with electrical impedance tomogrphy (EIT).  With bounded EIT (bEIT), we assume the geometry (from MRI) is known and need only to estimate the conductivity of each compartment.  Small currents are injected into the head, recovered in the EEG signal, and the difference in amplitude is related to tissue conductivity of the model with Ohm’s law.  My associates and I are exploring the possibility of understanding the pattern of cortical electrical fields through simulation, in which a whole brain artificial neural network model (thevirtualbrain.org) is created for to match the individual person’s fiber tractography (cerebral wiring diagram).  Each node modeling the cortex is used to generate a simulated EEG field in proportion to its dynamic activity in the network model.  Using machine learning to improve the emulation of the model of the individual’s cortical electrical fields over many weeks and months of recording, and extending the virtual brain with high performance computing, we will attempt to recreate the essential dynamics of the person’s brain in the artificial neural network model.  Applications to be evaluated will include neurological diagnosis, educational analysis and remediation, and sharing memory between neural and machine intelligence.

Host:  Mike Raymer

Catered Reception: 3:40pm-3:55pm, Willamette Hall, Paul Olum Atrium

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