at the University of Oregon
RNA folds. Proteins pump. Cells crawl. In these and countless other natural
phenomena, physical mechanisms are inseparable from biological
function. Biophysics strives to explore these connections between
physics, chemistry, biology.
Biophysics at the University of Oregon encompasses a wide variety
of groups spanning the Departments of Chemistry,
Physics, and Biology,
and the Institute of Molecular Biology,
Institute, Oregon Center for Optics,
and Institute for Theoretical
The list below briefly describes the "biophysical" faculty
at UO. Additional information can be found by clicking on the appropriate
links -- note especially the Biophysics Journal Club, about to
start its second action-packed year!
-   Andy Berglund -- Structural biology of RNA and Protein-RNA interactions in Muscular Dystrophy. [Web site]
-   Eric Corwin -- Single-molecule protein mechanics; emulsions and other soft matter. [Dept. page][Group web site coming soon]
-   Victoria DeRose -- Physical and chemical properties
of RNA, with emphasis on RNA catalysis and RNA-metal interactions. Construction
of novel metalloproteins. Spectroscopic methods including magnetic resonance
(EPR and NMR). [Web
-   Marina Guenza -- Conformational dynamics of proteins and protein-protein interaction. Theory, equilibrium and non-equilibrium statistical mechanics,
modeling and simulations. Theoretical predictions of NMR relaxation times of proteins, such as the signal transduction protein CheY. [Web site]
-   Andy Marcus -- Time-resolved electronic coherence spectroscopy
for studies of molecular dynamics in complex systems, including the
motions of electronic excitations in supercooled fluids, light harvesting
energy transfer complexes, and biological macromolecules in living cells.
-   Brad Nolan -- Structure and function of cytoskeletal proteins and their regulators using biochemical and biophysical techniques, with a focus on x-ray crystallography; establishing molecular bases for diverse cellular processes that require dynamic rearrangements of the cytoskeleton, such as endocytosis, exocytosis, cell motility and cell division.
-   Raghuveer Parthasarathy -- Physical properties of biomembranes and other biomaterials;
Advanced optical techniques, including optical trapping of microparticles and cells.
-   Ken Prehoda -- Mechanisms of protein-interaction based regulation; Structural biochemistry using x-ray crystallography and NMR. [Web site]
-   Jim Remington -- X-ray crystallography, visible light spectroscopy and protein engineering are used to probe the atomic structure and function of fluorescent proteins and to study the mechanism of action of enzymes. [Web
-   Pete von Hippel -- Protein-protein and protein-nucleic
interactions involved in the structure, assembly and function of 'macromolecular
machines', focusing particularly on DNA replication and RNA transcription
complexes. The group uses optical, chemical and theoretical biophysical
and biochemical tools and approaches in these studies. [Web
University of Oregon.
of images is strictly prohibited.
Maintained by Raghuveer Parthasarathy
raghu [at] uoregon.edu
Jan. 17, 2011